Apoptosis Induced by Pseudomonas aeruginosa in Antigen Presenting Cells Is Diminished by Genetic Modification with CD40 Ligand
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چکیده
منابع مشابه
CD40-independent engagement of mammalian hsp70 by antigen-presenting cells.
CD40 has been suggested previously to be a receptor for mammalian murine hsc73 (hsp70). We have examined, in vitro and in vivo, the role of CD40 in the interaction of murine dendritic cells and macrophages with hsp70, using several independent parameters including cell surface binding, translocation of NF-kappaB, stimulation of release of TNF-alpha, representation of hsp70-chaperoned peptides, ...
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Cellular interactions between antigen-presenting cells and activated CD4+ T cells are central to the regulation of adaptive immunity. Among the many receptor-ligand pairs involved, the critical importance of CD40-CD40 Ligand (CD40L) interactions has been demonstrated in many experimental systems. Dysregulation of antigen-presenting cell function is a hallmark of HIV-associated defects in cell-m...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 2002
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-200211000-00006